It has seemed to fall into one of two issues…
- Lastsession.xml
- Corrupt CascadeInfo.cas
- Close Navisworks
- Locate Lastsession.xml
- (XP default location) C:\Documents and Settings\**username**\Application Data\Autodesk Navisworks **product** 2010
- (Vista default location) C:\Users\**username**\AppData\Roaming\Autodesk Navisworks **product** 2010
- Delete the LastSession.xml
- Try and open Navisworks
http://usa.autodesk.com/adsk/servlet/ps/dl/item?siteID=123112&id=13894457&linkID=9241177
From what I’ve seen/heard, either one of these will usually fix Navisworks from not starting.